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Not everyone experiences fatigue, and the intensity can vary

The American Society of Anesthesiologists recommended in June that people who use GLP-1 agonists stop taking them for a week before surgical procedures because of the potential for gastrointestinal problems like nausea, vomiting and delayed gastric emptying that may "increase the risk of regurgitation and pulmonary aspiration of gastric contents during general anesthesia and deep sedation." Vomiting under anesthesia sometimes causes food and stomach acid to get into the lungs, which can cause pneumonia and other problems after surgery

Clinics may prescribe brand-name tirzepatide, such as Zepbound or Mounjaro, or rely on compounded alternatives