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However, when HtrA was overexpressed, this phenotype was restored (Ibrahim et al., 2004

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It is noted that, whether in vitro or in vivo experiments, the combination of harmine and Ex-4 can significantly promote the proliferation of human -cells compared with harmine alone, which may also be related to the promotion of trans-differentiation from -cells to -cells [44]

At the end of the treatment period, after euthanizing the animals, serum levels of LH, FSH, testosterone, insulin and glucose were analyzed, and histological, immuno-histochemical (IHC), and molecular examinations of the ovaries were performed