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Allergic Reactions: Risk of hypersensitivity reactions, which can be severe and life-threatening
discussion 352-335
In a 5-day phase 1 MAD trial where four groups of healthy volunteers received twice-daily or thrice-daily doses of GLY-200, decreases in glucose and insulin, along with increases in bile acids, GLP-1, peptide YY, and glicentin are noted in the cohorts with twice-daily dosing versus those receiving placebo (150)
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