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Brain Res 1664:18 Anderson BM, Hirschstein Z, Novakovic ZM, Grasso P (2020) MA-[d-Leu-4]-OB3, a small molecule synthetic peptide leptin mimetic, mirrors the cognitive enhancing action of leptin in a mouse model of type 1 diabetes mellitus and Alzheimers disease-like cognitive impairment
This ensures rapid absorption and immediate availability at the cellular level
Activation of these endothelial cells leads to disruption of nitric oxide (NO) signaling, vasodilation, and formation of a pro-atherogenic environment suitable for lipid deposition and plaque formation [14, 34]
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