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Commercial translation of this technology is exemplified by PureTech Health (founded 2001), which leverages MEVs within its preclinical Discovery platform for oral delivery of biologics (e.g., antisense oligonucleotides) and complex small molecules targeting rheumatoid arthritis, diabetes, autoimmune disorders, and oncology (Munagala et al., 2016
Some patients may need extra support for the continuance of healthy lifestyle behaviors, even with long-term use of pharmacologic agents
Target trial emulations of GLP-1 and dual GLP-1/GIP agonists to reduce major adverse liver outcomes in type 2 diabetes
These proteins are found in areas of your brain that regulate appetite
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