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It effectively suppresses pro-inflammatory mediators, such as nitric oxide (NO), IL-6, TNF-, IL-1, and IL-8, as reported in macrophages stimulated by lipopolysaccharides (LPS) and human dental pulp cells exposed to inflammatory stimuli
(2024) 10(6):eadj2752
Dupixent also led to statistical improvements in post-bronchodilator forced expiratory volume levels from baseline at week 12, satisfying the trials secondary endpoint
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