The reaction looks alarming: redness, sensitivity, small bumps, sometimes acne-like breakouts
Yet only 4 to 6% of participants discontinued the drug in these trials, mostly owing to these GI side effects (and 1-2% in the placebo group discontinued the study drug for the same reasons)
Statistical analysis Statistical analysis was performed using R version 4.3.1 (R Core Team, Vienna, Austria) with the tidyverse, survival, survminer, MatchIt and mice packages
Nitrated HGF ( bar 3 , peroxynitrite-treated at 1:2000) lost its activation activity as demonstrated by a drop in the activation index down to the baseline level observed in the negative-control culture ( bar 1 ) 32 and in GSSSG/LASSS-cultures ( bars 6 and 10 , missing HGF)