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Despite producing more weight loss, tirzepatide had lower rates of treatment discontinuation due to gastrointestinal adverse events (2.7% vs 5.6% for semaglutide)
doi: 10.1007/s12012-021-09656-z 34 BorgesNAStenvinkelPBergmanPQureshiARLindholmBMoraesCet al
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Moreover, as opposed to other animal models, rats on the fcHFHS diet also show specific human like characteristics such as persistent hyperphagia, snacking behavior (i.e., increased meal frequency without reducing meal size) and increased motivation behavior (even in sated animals
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