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Flavonoids can prevent the formation of damaging radicals, such as hydroxyl radicals formed via the Fenton reaction by the chelation of redox-active metals (copper, iron, manganese) (Simunkova et al
But push those conditions outside acceptable ranges and the copper can dissociate from the peptide, leaving you with two separate, inactive components
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The resulting metabolite levels were then normalized to those from matched distal nontumor samples from the same patients, and logtransformed
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