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Efpeglenatide Efpeglenatide is a novel, long-acting GLP-1 receptor agonist developed by Hanmi Pharmaceuticals (South Korea) utilizing the proprietary LAPSCOVERY (Long-Acting Protein/Peptide Discovery) technology platform

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In fact, platelet-activating factor binding to PAFr leads to the production of inositol trisphosphate (IP3) through the phosphatidylinositol cycle, which in turn binds to inositol 1,4,5-triphosphate receptor type 1 (IP3R1) to induce the release of Ca 2+ stored in the endoplasmic reticulum (Kroegel et al., 1989

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