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A critic to the use of a murine model deficient for intestinal GCG products, would be that other gut hormones might compensate for the lack of a functional GCG gene in that tissue, hence explaining the normalized incretin effect
The activity of Retatrutide has been evaluated in several randomized phase 2 clinical trials, demonstrating significant weight reduction
Speculation is labeled as such
Detailed results will be submitted to a peer-reviewed journal and presented at ObesityWeek 2024, which will take place November 3-6.
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