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NNMT inhibition increases adipose [S-adenosylmethionine (SAM)] and [Nicotinamide adenine dinucleotide (NAD+)] levels As youll discover later on in this article, theres a good reason why increased production of SAM and NAD+ within fat cells is beneficial
Other options may be preferable for people who: Require human clinical trial evidence on the finished product
They reduce homocysteine levels, which, when elevated, can increase the risk of osteoporosis
However, the lack of extensive studies and FDA approval for weight loss specifically may deter some patients
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