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GLP-1 reduces food cravings partially by decreasing activity to the anticipation of food in the left insula of obese patients with diabetes and may inhibit overeating by increasing activity to the consumption of food in the right OFC of obese and left insula of obese with diabetes

Colbert explains GLP-1 medications as a three-lever tool: they influence appetite signaling in the brain, slow gastric emptying in the gut, and improve blood sugar regulation through insulin-related pathways

Peroxiredoxins Prxs are a ubiquitous family of antioxidant enzymes that regulate peroxide and peroxynitrite levels in mammalian cells (Sanchez-Font et al., 2003)

Non-time-sensitive medications can be taken as usual, but if nausea worsens, separate from meals