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Instead, consistency was judged pragmatically through clinical transitivity, inspection of network geometry, comparison of random-effects and fixed-effect results, and deviance-based model fit diagnostics
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On PND 10, all animals underwent the olfactory discrimination test ( n = 10 animals/group)
In SURMOUNT-1, tirzepatide showed mean losses that reached about 20.9% at 72 weeks at the highest dose studied
The team emphasizes that despite these differences, both medications require gradual dose escalation, consistent adherence, and lifestyle changes for best results
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