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Conclusion The review concludes that altered eating experiences during GLP-1RA therapy are more consistent with changes in food reward, hedonic evaluation, and motivational drive than with a uniform impairment of taste function, although peripheral taste-pathway modulation may contribute in some cases

Varanasi A, Patel P, Makdissi A, Dhindsa S, Chaudhuri A, Dandona P: Clinical use of liraglutide in type 2 diabetes and its effects on cardiovascular risk factors

The smart move is to keep an eye on the TRIUMPH data as it releases, and in the meantime, make progress with the clinically proven options that are already available and working right now

Melatonin production declines with aging [34], possibly due to age-related calcification of the pineal gland [35], rather than increased clearance [34]