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L-carnitine and alpha lipoic acid Alpha lipoic acid is a sulphurous fatty acid that acts as an antioxidant and can protect cells from free radical damage

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Five positions judged to govern ketosteroid isomerase activity based on mutational studies ( The catalytic efficiency of HsaGST A3-3 with 5-AD is 5000-fold higher than that of HsaGST A2-2, and we found that mutating the five residues in the H-site of HsaGST A2-2 into the corresponding HsaGST A3-3 residues enhanced the efficiency to 70% of the HsaGST A3-3 value (Table 1)

Kodama H, Yamaguchi R, Fukuda J, Kasai H, Tanaka T