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At room temperature, the intermediate (4.433 mmol) was dissolved in 30 mL of dimethylformamide, and 4.873 mmol of 2-aminobenzenethiol was added, and the reaction was carried out at 150 C for 3 h
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The key takeaway from the researchers was that mitigation strategies, specifically higher protein intake and resistance exercise, should be recommended as standard practice for all patients on these medications
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