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doi:10.1002/ajmg.c.30087

By targeting multiple mechanismssuch as enhancing insulin secretion, suppressing glucagon release, slowing gastric emptying, and promoting satietyGLP-1 RAs provide significant improvements in glycemic control, weight reduction, and long-term cardiovascular and renal health (6)(16)(23)

102 Hence, insulin indirectly reduces gastrointestinal motility, appetite and gastric acid secretion due to its suppression of ghrelin

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