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Cell, 2017
Damaged cells within the tendon dont have time to recuperate
Instead of shaking the vial, swirl it slowly until the powder is completely dissolved, as shaking can damage the delicate peptide structures
Here, we determine structures of cagrilintide bound to Gs-coupled, active, amylin receptors (AMY 1 R, AMY 2 R, AMY 3 R) and calcitonin receptor (CTR) and compare cagrilintide interactions and the dynamics of receptor complexes with previously reported structures of receptors bound to rat amylin, salmon calcitonin or recently developed amylin-based peptides
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