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The trial demonstrated a 20% reduction in the primary composite endpoint of cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke (hazard ratio 0.80, 95% CI 0.72-0.90).[1] The trial also demonstrated improvements in multiple cardiovascular biomarkers independent of weight loss
Conclusions These findings suggest that microglial GLP-1R activation in the TNC may suppress the central sensitization of CM by regulating TNC microglial activation via the PI3K/Akt pathway
This timeline is based on clinical data and real-world patient experience
Understanding what your semaglutide should look like also helps catch storage issues while traveling
