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This suggested approach involves exploring small-molecule inhibitors of NLRP3, along with strategies that modulate upstream or downstream components of the inflammasome pathway [240]
Dietary counseling and structured exercise programs should be incorporated into comprehensive care plans
Fourteen percent of participants had diabetic retinopathy at baseline (most mild non-proliferative), and the rates of retinopathy progression during the study were low (6% and 8% with orforglipron and 7% and 8% with semaglutide), with no significant difference between groups
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