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(1) Common symptoms include: Fatigue Flu-like symptoms including fever, hot flashes, and chills Joint pain Back pain Headaches One of the hallmark signs of acute Lyme disease is the development of a distinctive red, circular rash often resembling a bulls-eye, known as erythema migrans
The first and rate-limiting step involves generating the dipeptide -glutamylcysteine (-EC) from glutamate and cysteine, catalyzed by glutamate cysteine ligase (GCL)
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