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Challenges Due to its well-established role in neural tube development, folic acid supplementation is recommended in clinical guidelines (US Preventive Services Task Force, American College of Obstetricians and Gynecologists, American Academy of Family Physicians, American Academy of Pediatrics, and the Center for Disease Control and Prevention) for those who are planning to or could become pregnant (Force et al., 2023)

J Pharm Sci 93:21842204

Therefore, the concentration of H 2 O 2 in the cell supernatant was further detected using assay kits