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The findings, which showed that these events were rare but significant, particularly in patients using the drugs for weight loss, were published in the Journal of the American Medical Association (JAMA)
Additionally, the therapeutic benefits of thiazolidinediones, a class of drugs that activate the peroxisome proliferator-activated receptor gamma, are largely attributed to their ability to induce adiponectin
Glucagon is a hormone that normally raises blood sugar levels by promoting the production of glucose in the liver
In integrated transcriptomic and single-nucleus RNA sequencing (snRNA-seq) analyses, necroptosis was identified as a highly enriched RCD pattern in DKD tubules, defining distinct patient subtypes that correlate closely with chronic inflammatory responses and macrophage infiltration (229)
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