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None of the participants experienced a serious adverse event as defined by the European Medicines Agency (EMA) (24), and no confirmed case of acute pancreatitis was found
Remote review of side effects and CGM reports was performed at days 7, 21, 32, 56, 63 and 77 (2 days) of the dose titration periods, and additionally as prespecified in the study protocol, as needed per the research teams judgment
5 Various esters and amides of GSH are transported into cells, but some have toxicity caused by cleavage products such as methanol, ammonia, and alcohols
The mechanisms underlying weight regain are multifactorial and include metabolic adaptation with decreased energy expenditure, hormonal changes affecting appetite regulation, anatomical alterations such as gastric pouch or stoma dilation, and psychosocial factors including maladaptive eating behaviors
