It is also worth considering that patients with diabetes are at increased risk of oral health problems, including fungal infections (oral candidiasis) and periodontal disease, which may be mistaken for drug-related side effects
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GLP-1s were associated with lower risk of complications for those already having a substance use disorder Among people who already had a substance use disorder, starting a GLP-1 medication was associated with fewer substance-related emergency department visits, hospital admissions, overdose events, episodes of suicidal ideation or attempts, and lower mortality (see graph below)
SGLT-2 inhibitors, such as empagliflozin, canagliflozin and dapagliflozin, are considered to have intermediate efficacy for glycemic control, and are associated with weight loss and a low risk of hypoglycemia [6]