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The first is that the dietary shift isnt substitution, its contraction: GLP-1 users arent simply swapping chips for protein bars, theyre also buying less food overall, and the yogurt and nutrition-bar gains, while real, were modest compared to the scale of the overall grocery decline
16 weeks ~20 syringes 1 tirz/week from Week 1
What the new JAMA Surgery study shows The JAMA Surgery research study compared bariatric metabolic surgery to GLP 1 receptor agonist (GLP 1 RA) therapy for treating obesity in adults who had class II and III obesity
These data showed that subchronic (7 to 14 days) exendin-4 or liraglutide administration in rodents resulted in hyperactivation of the HPA, disruption of glucocorticoid circadian secretion, hypertrophy of the adrenal gland, and dysregulation of pituitary-adrenal stress responses [77]
