53 Since the majority of cells express ERs, estrogen actions influence almost all tissues and are responsible for: a) homeostatic regulation, b) cell proliferation and apoptosis, c) liver protein expression, d) lipid metabolism, e) energy balance, f) glucose metabolism, g) immune and cardiovascular alterations, h) gonadotrophin feedback and gametogenesis, i) brain-neuronal development/memory processing and repair/neurodegeneration, j) bone growth, etc., 7,15,53,60 including estrogens positive (agonist) or negative (antagonist) actions on skin, especially in women
Minoxidil causes scalp irritation, unwanted body hair growth, and requires twice-daily application forever (if you dont use it, you lose it) Finasteride blocks 5-alpha reductase systemically, which means it can crush your DHT levels, destroy your libido, cause erectile dysfunction, and (in some men) trigger long-lasting post-finasteride syndrome even after discontinuation
When we talk about "elevated liver enzymes," we are usually referring to specific proteins that the liver uses to trigger chemical reactions
Frontiers in Neuroscience, preliminary reports