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The authors compared breast cancer incidence among 15,264 women with prior GLP-1 exposure 1 to the same number of women without exposure, with matching for age, BMI, breast density, race, ethnicity, and history of diabetes
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In a mouse model of endotoxemia, LPS rapidly induced S100A8/A9 release and acute cardiac depression, while genetic deficiency of S100A9 or pharmacological blockade of S100A8/A9 with ABR-238901 prevented or reversed myocardial dysfunction and reduced systemic inflammation (Jakobsson et al., 2023)
Skin cells take roughly 28 to 40 days to turn over, and the "melanin switch" happens at the base layer of the skin
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