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Researchers running dose-response work should reference the COA molar values directly when calculating administered nmol/kg

In recent years, global transcriptome profiling using bulk or single-cell RNA-sequencing (RNA-seq) has enabled the discovery of distinct splicing patterns in the brain compared with non-neuronal organs 4,5,6 , in neurons compared with non-neuronal cells in the brain 7,8 , in central nervous system (CNS) neurons compared with peripheral sensory neurons 9 , as well as across different developmental stages in the brain 9

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