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Abbasi B, Dong Y, Rui R

Histone deacetylases (HDAC2), a member of the HDAC family, is correlated with insulin signaling components in postsynaptic glutamatergic neurons of the adult mouse hippocampus, and hyperactivity of the HDAC system (including HDAC2) may result in the suppression of the insulin signaling system and consequent disruption of synaptic plasticity in type 2 diabetes

The growing economic impact of GLP-1s will, in turn, require the healthcare industry to come up with new financial models, the authors of the report argued