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The gut microbiome influences many aspects of metabolic health including digestive signaling, short-chain fatty acid production, immune communication, and gut barrier integrity
10.1038/379069a0 103 VuceticZ.KimmelJ.ReyesT
It appears to do this through several mechanisms including upregulation of growth factors involved in mucosal repair, reduction of inflammatory mediators, and support of gut barrier integrity
Effects of weight loss in overweight/obese individuals and longterm lipid outcomesa systematic review
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