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As a naturally occurring tripeptide complexed with copper ions, GHK-Cu serves as an important compound in peptide-based biochemical research
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A premature leptin surge or excessive leptin, such as can occur with in utero growth restriction or with obese or hyperleptinemic dams, can also disrupt this connectivity and result in a subsequent insensitivity to satiety signals (Yura et al., 2005
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