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When recruited, it becomes oligomerized and is transported to mitochondria where it interacts with protein adaptors, such as the mitochondrial fission factor (Mff), the mitochondrial fission protein 1 (Fis1), the mitochondrial dynamics protein 49 (MiD49/MIEF2), and the mitochondrial dynamics protein 51 (MiD51/MIEF1) [315]

In formal development, that kind of caution is non-negotiable

The drugs, originally designed to treat diabetes and found to promote weight loss, have also shown benefits for heart risks, sleep apnea and alcohol and substance abuse

doi: 10.1038/s41467-022-30272-0 Summary Keywords Salmonella , gentamicin, cystine, resistance, metabonomics Citation Du J, Wu Z, Zhu C, Yang H, Zhao F and Fang B (2025) Exogenous cystine increases susceptibility of drug-resistant Salmonella to gentamicin by promoting oxidation of glutathione metabolism and imbalance of intracellular redox levels