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Interestingly, changes in calcium homeostasis in the brain may contribute to the cognitive decline associated with normal aging and possibly to the development of neurodegenerative disorders (61, 62)
doi: 10.1111/JOIM.12783 32 GerritsA
They are not illegal to buy or own - and widely available online - but they are not approved for human use, so are not subject to the quality controls that govern pharmaceutical manufacturing
Glutathione decreases as we age and can also decrease with some environmental factors such as stress, infection, poor diet, or chronic disease (source)
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