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As a result, controlling cellular uptake of NPs in relation to ligand density has gained increasing interest in the nanomedicine field, in particular regarding the choice of the most appropriate linker molecule involved in the polymer-ligand conjugation: latest researches have revealed that higher NP internalization occurs with shorter linker length (Abstiens et al., 2019)
The presence of diabetes, atherosclerosis, and heart disease are additional risk factors
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