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The mean baseline BMI of participants was 31.8 kg/m2, and Mazdutide was administered at various doses: 3 mg, 4.5 mg, and 6 mg
Side effects tend to be mild
Wegovy (semaglutide) weekly injection dosing schedule The dosing schedule of Wegovy is as follows: Weeks 1-4: 0.25 mg once weekly for the first 4 weeks Weeks 5-8 : 0.5 mg once weekly Weeks 9-12 : 1 mg once weekly Weeks 13-16: If tolerated, increase to 1.7 mg once weekly Weeks 17 onwards : If the dosage needs to be escalated further, increase to 2.4 mg once weekly, which is the maximum dosage
DIO mice were randomized to treatment according to body weight (n = 15 per group) and dosed subcutaneously (5 ml/kg) for a total of 28 days with vehicle (QD), liraglutide (0.2 mg/kg, BID) or GUB09-145 (0.04 mg/kg, BID)
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