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New therapeutic strategies focus on MATs approaches, including MitoQ, Mito-TEMPO, and nano-Mito-PBN (Pang et al., 2025
Complexity increases with additional stack components, requiring careful attention to interactions, timing, and individual response assessment
This separation provides theoretical safety, though the combination remains unstudied in formal clinical trials
Its structure consists of a D-retro-inverso (DRI) modified segment derived from the forkhead domain of the FOXO4 transcription factor, fused to a cationic cell-penetrating peptide (CPP) sequence
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