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Ipamorelin also supports sleep through increased GH production, though the evidence base for sleep-specific effects is less extensive than for GHRH analogs
The role of GLP-1 in the nervous system largely, but not exclusively, complements peripheral actions of this peptide and encompasses suppression of food and water intake and the reduction of appetite and food reward
In the small intestine, it increases the secretion of incretin hormones (like GLP-1) in response to nutrient ingestion
This means that it binds to the same receptors as does endogenous ghrelin (the GHSR-1a receptors) and that it stimulates the cells in the pituitary gland to release more GH without raising ACTH or cortisol levels [3]
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