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175 For the PPP enzymes, recent studies have discovered some inhibitors targeting on G6PD, such as NADP + analogs, the competitive inhibitor 6-aminonicotinamide (6-AN), noncompetitive inhibitors epiandrosterone and dehydroepiandrosterone (DHEA) which reduces the availability of NADPH and inhibits the cell growth
5-Amino-1MQ 5-Amino-1MQ is a small-molecule compound and NNMT inhibitor available in lyophilized form for laboratory research
an FDA advisory committee rejected adding it to the approved compounding list in 2024, citing toxicity and an unresolved cardiac signal
Ye Q, Jin X, Zhu B, Gao H, Wei N (2023) Lanmodulin-functionalized magnetic nanoparticles as a highly selective biosorbent for recovery of rare earth elements
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