Dysregulation of autophagy, endolysosomal trafficking, lysosomal function, and mitochondrial integrity not only promotes neuronal dysfunction and death but also contributes to protein aggregation, neuroinflammation, and disease propagation across neural networks
Although the study was not designed to adequately test for between-group differences in change, we explored differences in between-group effects on GSH concentration using linear mixed models
In animal studies, P21 has been shown to boost levels of BDNF (brain-derived neurotrophic factor), thus promoting neurogenesis (nerve growth) and inhibiting the formation of Amyloid plaques and Tau proteins seen in Alzheimer's disease
"In the past, if I had lost weight, I got a self-esteem boost, which is almost like dopamine