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More importantly, accumulating evidence has established that c-Myc can modulate miRNA transcription by directly binding to their promoter regions [42,43,44,45,46,47]

Moreover, most of the existing preclinical studies have relied on male rodents, neglecting sex-specific variants in gut microbiota compositions and neuroinflammatory responses (Chakraborty et al., 2025)

Evidence is limited, but precaution is warranted for individuals on multiple medications

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