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GLP-1 appears to attenuate the process of neuroinflammation and protects neurons and glia under oxidative stress conditions in the depressive brain
In: The metabolic and molecular bases of inherited disease, 8, 67174 Jun DW, Cho WK, Jun JH, Kwon HJ, Jang KS, Kim HJ, Jeon HJ, Lee KN, Lee HL, Lee OY, Yoon BC, Choi HS, Hahm JS, Lee MH (2011) Prevention of free fatty acid-induced hepatic lipotoxicity by carnitine via reversal of mitochondrial dysfunction
The GSH concentration declines slowly over the 48 hour period to about 50% of normal and the rate of GSH export declines to 67% of normal consistent with the experiments reported in [33]
In addition to suppressing appetite, GLP-1 agonists block the action of glucagon, a hormone that signals the liver to release glucose into the bloodstream, thus increasing blood sugar levels
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