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However, patients who may be at higher risk for wet age-related macular degeneration, such as older adults, should be aware of the possibility of new visual symptoms. The exact reasons are unknown, but one explanation is that if blood sugar drops too quickly or too sharply in certain patients, this may unexpectedly affect the retina the light-sensitive tissue at the back of the eye, which contains GLP-1 receptors, the authors say
10.1042/CS20171299 61
The structural damage from freezing is not always visible, but it can reduce efficacy and potentially cause adverse reactions from aggregated proteins
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