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Some of the medical conditions that can cause low platelet levels primary immune thrombocytopenia (ITP), which is an autoimmune disease other autoimmune diseases, such as lupus infections, such as with the hepatitis C virus (HCV), HIV, or the mumps virus certain medications long-term alcohol misuse pregnancy, especially the pregnancy complication HELLP syndrome, which refers to hemolysis, elevated liver enzymes, and low platelets some nutritional deficiencies inherited conditions, although this is more common in children than adults In this article, we look at the treatment options for thrombocytopenia, including blood and platelet transfusions, medications, surgery, and more