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Patients with high-responding genetic profiles may reach goals on lower doses, while those with less-responsive variants can switch early to dual-compound protocols like GLP-Squaredavoiding wasted time and unnecessary dose escalation based on guesswork
Bradley, D
Meta-Analysis of Association between TCF7L2 Polymorphism Rs7903146 and Type 2 Diabetes Mellitus. BMC Medical Genetics, vol
However, when assessed by IPGTT, chronic exendin-4 treatment at this dose failed to exert significant effects on glucose tolerance, whereas exendin-phe1 remained effective (Fig
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