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Both GLP-1 (7-36) and GLP-1 (7-37) also play roles in gastric motility (gastric emptying), on the suppression of plasma glucagon levels (glucose production) and possibly on the promotion of satiety and stimulation of glucose disposal in peripheral tissues independent of the actions of insulin

Tirzepatide is used as a GIP/GLP-1 comparator

This effect is mediated, at least in part, through attenuation of CXC motif chemokine ligand 1 (CXCL1) signaling, which regulates signal transducer and activator of transcription 1 (STAT1) and STAT3 phosphorylation, particularly in hematologic malignancies [124-126], and upregulation of immuneregulatory microRNAs, such as miRNA-50 and miRNA-155 [127]

Its important to emphasize that serious adverse effects are uncommon