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However, a separate Phase 3 study in paediatric patients showed clinically meaningful overall survival, prompting AstraZeneca to proceed with regulatory submissions for the paediatric indication while continuing discussions with health authorities regarding the adult program
The RT-qPCR results showed that cell sorting operation dramatically increased the apparent expression level of the ATP6AP1L gene in the enriched cells with both expression plasmids (Figure 6B)
Therefore, exposure to direct sunlight or fluorescent lighting can diminish its effectiveness
Histopathological scoring revealed significant portal congestion, periportal inflammatory infiltrate, and hepatocyte necrosis compared to CTRL (Figures 8BD)
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