Normal levels of GSH have been shown to have roles in restricting serine availability to preserve regulatory T cell (Treg) functionality (Kurniawan et al., 2020)
The Phase IIb efficacy trials did not meet their efficacy endpoints, and clinical development for the original therapeutic indication was halted
Se excess can further lead to joint pain, muscle weakness, tremor, muscle spasms, ataxia, headache, confusion and memory loss, and, in more severe cases of intoxication, fever, hypotension, abnormal electrocardiogram, cardiac arrest, respiratory arrest, liver toxicity, delirium, coma, and death (51, 65, 66)
Ce processus est crucial pour prvenir le vieillissement prmatur et la dgnrescence cellulaire