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It's not a magic bullet, but it may offer layered support for those seeking consistency, resilience, and accelerated return-to-training timelines
Indeed, several clinically relevant engineered BoNTs, such as targeted secretion inhibitors, omit the H C domain entirely and retain efficacy 70,71
The tissue lacks the robust blood supply that muscles enjoy, receives constant mechanical loading that disrupts healing, and often develops fibrotic scar tissue rather than healthy organized collagen
Drug resistance resulting from kinase dimerization is rationalized by thermodynamic factors describing allosteric inhibitor effects
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